Parul Saini, Anoop Kumar, Pankaj Sharma, Sharad Visht
Oral fast disintegrating films (OFDF) is an emerging technology brings out “formulations taken without water” with quick onset of action and improved patient compliance. Oral films provide better drug utilization in by-passing the first pass metabolism, enhance drug bioavailability, mask the bitter taste of the drug and do not need water to swallow. OFDF formulations are suitable for cough, cold remedies, sore throat, allergenic conditions, nausea, pain and CNS disorders. Multivitamins, caffeine strips, snoring aid and sleeping aids are also applicable for incorporation in the oral films. The major constraints of OFDF are limited drug aqueous solubility, poor permeability and its high dose. Present article overview the advancement in the oral dosage forms, application, formulation consideration, method of preparation, evaluation, marketed product and patented technologies of oral fast disintegrating films.
