Ezeani Obinna Emmanuel*
Despite the growing success in global e-health and transition of most health care system to a more accessible form of health care for all (e-health), not all countries or parts of the world find it easy to adopt this trending health format. Most countries are posed with huge challenges with e-health transition. This study is aimed to highlight some challenges faced by most countries especially the Low-and Middle-Income Countries (LMIC) in Africa, using Nigeria as a model in the transition to and adoption of e-health. There are a number of possible limitations/barriers to the adoption and full scale implementation of e-health in Nigeria, some which include; Poor leadership and governance, Legislation, Policy and Compliance, Infrastructure, and Workforce etc. Thus for a full scale implementation of e-health the aforementioned must be properly considered and solution proffered. Some of such solution may include implementation of a robust nationwide implementation of Electronic Medical Records (EMRs) both in the primary health care centers and all health care outlets in the nation, regular dissemination of the right health information to a targeted population (caregivers, patients, etc.) through designated medical apps, and so many others.