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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 51
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Abstract

Comparison of in vitro antioxidant potential of fractioned Paederia foetida leaf extract

Silpi Chanda, Sayeed Ahmad,Kuldeep Singh

Objective: The aim of this study was to investigate the antioxidant activity of different fractionated extracts of leaves of Paederia foetida by DPPH* scavenging assay and phytochemical analysis of the methanolic extract of the leaf. Materials and Methods: The fresh leaves of P. foetida was extracted by using methanol and then proceed for solvent fractionation. The extract was tested for phytochemical analysis and antioxidant activity using DPPH* scavenging assay. Results: Methanolic extract showed the presence of triterpenoids, volatile oil, sterols, alkaloid and glycoside. The yield of methanolic extract was 36%w/w which showed the highest antioxidant activity as compared to other fractions. Conclusion: Paederia foetida leaf extracts possessed free radical scavenging activity