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Abstract

Evaluation of the Performance Characteristics of Influenza A+B Rapid Test for Point-of-Care Diagnosis Compared with RT- PCR Method

Zhang Lei*, Yang Feng and Zhu Junzhe

Influenza, commonly referred to as the flu, is a highly contagious respiratory viral infection that spreads through aerosolized droplets resulting from coughing and sneezing. This communicable disease predominantly manifests during the fall and winter months. Type A influenza viruses exhibit higher prevalence compared to type B viruses and correlate with more severe epidemics. The rapid and accurate diagnosis of influenza A and B viral infections is crucial for early treatment and preventing further spread.

The Influenza A+B Rapid Test Cassette, developed by Hangzhou AllTest Biotech Co., Ltd is a lateral flow immunoassay for the detection of influenza A and B antigens in nasopharyngeal swab, throat swab, or nasal aspirate specimens. Its performance has been evaluated using patient specimens, with Reverse-transcription polymerase chain reaction (RT-PCR) as the benchmark reference method. The Influenza A+B rapid test cassette evaluated in this study demonstrated high sensitivity and specificity, comparable to RT-PCR, making it a valuable alternative to traditional laboratory diagnostic methods. By offering a quick and easy-to-use screening tool, this point-ofcare test (POCT) facilitates rapid diagnosis of influenza A and B viral infections.

The development and advancement of rapid diagnostic tests targeting influenza A and B viral infections play a pivotal role in improving patient outcomes and mitigating transmission rates. The Influenza A+B rapid test cassette is a reliable and efficient tool for rapid detection of influenza viruses, allowing for prompt treatment and control of outbreaks.

Keywords

Influenza A; Influenza B’; Rapid test; RT-PCR

Published Date: 2023-08-31; Received Date: 2023-08-01