The aim of systems biology is to provide a system or multilevel understanding of biological processes through the integration and modeling of different data sources. The complexity of immunology and infection of microorganism cannot be untangled by investigating it from a reductionist point of view. Therefore immunology and infection microbiology, with all its complex interactions between different species, different cell types, different regulatory and signaling pathways, and different molecules and genes, which always could not be measured directly by experiments in wet lab, provides a perfect environment for the development and use of approaches based on systems biology.
