In Vitro Antioxidant activity of Metabolite from Streptomyces
fradiae strain GOS1
Gautham S A, Onkarappa R
Streptomyces species being the largest members of actinomycetes have been known for their metabolic capacities and form an august source of pharmacologically important compounds. The present study concentrated on in vitro evaluation of antioxidant property of n-butanol extract with antimicrobial potential from Streptomyces fradiae strain GOS1. The antioxidant activity was evaluated by total phenolic content, total reductive capability, DPPH assay, lipid peroxidation inhibition assay, nitric oxide scavenging activity, super oxide anion scavenging activity and metal chelating activity. The result showed moderate dose dependent antioxidant activity of the metabolite and is indicative of its role as a primary antioxidant.
