Myasthenia Gravis: Challenges and Therapeutics Solution
Sandeep Kumar Singh, Vijay Kumar and Ashok Kumar
Myasthenia gravis (MG) is an autoimmune disease leading to fluctuating muscle weakness and fatigability and patients have autoantibodies against the acetylcholine receptor. MG is a postsynaptic dis¬order caused by the antibody-mediated destruction of acetyl-choline receptors (AChRs) and blockage of the binding of acetylcholine to acetylcholine receptor. Lambert-Eaton myasthenic syndrome (LEMS) is distinct autoimmune disorders that affect neuromuscular transmission. A study by Jee-Ae Kim et al. showing same clinical features and electrophysiological finding in patients of MG and LEMS
