SOX4 Gene Contributes in Induction of Uterine Adenomyosis
Mahdi Saber Al-Deresawi1* , Abdul Hussein Moyet AlFaisal2 , and Aseel Razaq Al-Rekabi2
The objective of this study was to determine the level
expression of SOX4 gene and its role in induce adenomyosis.
Tissues specimens (30 patients and 10 healthy groups).
Histological study of all tissues was carried out to observe
the changes in tissues. Thirty biopsies of hysterectomy were
concluded in this study. The expression levels of SOX4 gene
were estimated by QRT-PCR. This study recorded the mean
folding of SOX4 was a highly significant increased (p<0.01) in
patients with adenomyosis (6.96 ± 0.27) when compared to
the healthy control group (1.00 ± 0.00). We concluded the
high expression of SOX4 gene had a role in development the
uterine adenomyosis.
