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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 51
  • Journal CiteScore: 46.50
  • Journal Impact Factor: 26.99
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Citations : 12061

International Journal of Drug Development and Research received 12061 citations as per Google Scholar report

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Abstract

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SCHIFF BASE DERIVATIVES

DEMIR MÜLAZIMOÐLU AYªENA, ÖZKALP BIROLB AND MERCIMEK BEDRETTINA

In this study, Schiff base ligands were synthesized, characterized and investigated of antibacterial activities on five bacteria. 2-((4-benzyloxy-benzylidene)amino)phenol derived from 4-benzyloxybenzaldehyde and 2- aminophenol. (4-benzyloxy-benzylidene)pyridine-2-yl-amine derived from 4-benzyloxy-benzaldehyde and 2- aminopyridine. The Schiff bases were characterized by elemental analysis, FT-IR and 1H-NMR. The Schiff bases were screened for in-vitro antibacterial activities by disc diffusion and broth microdilution techniques. The minimum inhibitory concentration (MIC) values were calculated by microplate reader at 620 nm. It was found compounds showed mild to moderate antibacterial activity by disc diffusion technique.