Sheikh Shoib, Javid Ahmed Malik and Ilham Zaidi*
Objective: Research on the connection between depression and Obstructive Sleep Apnea (OSA) has not been particularly focused. This study looked into possible links between continuous positive airway pressure, or CPAP, and depression in people with OSA.
Methods: Between July 2011 and August 2013, 47 inpatients with OSA who were referred from various specialty clinics underwent polysomnography testing. The patients were assessed using the Mini International Neuropsychiatric Interview (MINI plus). The Montgomery Asberg Depression Rating Scale (MADRS) was employed for follow-up evaluations among patients who had received a diagnosis of depression. In this study, the effect of CPAP on depressive symptoms in individuals with OSA was evaluated at baseline, three months, and six months following the initiation of therapy.
Findings: When comparing pre-CPAP and the conclusion of the CPAP course by 9.1, the 3-month follow-up by 14.4, and the 6-month follow-up by 18.7 (all p < 0.01), there were notable differences in the mean MADRS scores.
Conclusions: Following CPAP treatment, many OSA patients saw a considerable reduction in their MADRS scores. CPAP's ability to lessen depressive symptoms raises the possibility that mood disorders in individuals with OSA are not solely caused by physical symptoms. The amount of evidence demonstrating the connection between depression and OSA is increased by this study.
Published Date: 2024-03-14; Received Date: 2024-01-22
