Image - (2015) Volume 3, Issue 3
| Issam Lalya*, Hassan Sifat, Khalid Hadadi Mansouri Hamid Department of Radiation Therapy, Military Teaching Hospital Mohammed V, Rabat, Morocco |
| Corresponding Author: Issam Lalya, Department of Radiation Therapy , Military Teaching Hospital Mohammed V, Rabat, Morocco, Tel: 00212661572770, E-mail: issamlalya@yahoo.fr |
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Rhabdomyosarcoma (RMS) is a highly malignant neoplasm that arises from embryonic mesenchyme [1]. It is the most common soft tissue tumour in children, with the head and neck region accounting for 35-40% of cases [2]. Para meningeal (PM) rhabdomyosarcomas are tumors that arise from sites adjacent to the meninges, including the nasopharynx and nasal cavity, middle ear and mastoid, para nasal sinuses, pterygopalatine and infratemporal fossa. They have a propensity for central nervous system extension and poorer survival than the others rhabdomyosarcoma.
| Rhabdomyosarcoma (RMS) is a highly malignant neoplasm that arises from embryonic mesenchyme [1]. It is the most common soft tissue tumour in children, with the head and neck region accounting for 35-40% of cases [2]. Para meningeal (PM) rhabdomyosarcomas are tumors that arise from sites adjacent to the meninges, including the nasopharynx and nasal cavity, middle ear and mastoid, para nasal sinuses, pterygopalatine and infratemporal fossa. They have a propensity for central nervous system extension and poorer survival than the others rhabdomyosarcoma. The presentation in the nasopharynx is very rare only few cases have been reported in the literature [3]. External beam radiotherapy is an integral component of treatment for nasopharyngeal RMSs [2].We report the case of an Arabian 6 year old boy, presented to our institution for a 6 months history of nasal obstruction and right cervical lymphadenopathy. Nasopharyngeal endoscopy with biopsy showed a mass involving the entire nasopharynx. Histologic analysis revealed embryonic rhabdomyosarcoma. Magnetic resonance imaging showed an organic process of the nasopharynx invading parapharyngeal spaces, the pterygoide processes, prevertebral and retrostyloid spaces without intracranial extension (Figure 1 and Figure 2). Work-up including chest and abdomen CT scan and bone scintigraphy was normal. The patient received 8 cycles of VAC (Vincristine, Adriamycin, Cyclophosphamide) followed by radiation therapy at the dose of 50, 4 Gy. The first MRI of assessment showed a complete response. | ||||
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