Department of Pediatrics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil
Research Article
Zinc Supplementation in the Management of Acute Diarrhea in High-Income Countries ? A Systematic Evaluation and Meta-Analysis
Author(s): Túlio Revoredo, Lucas Victor Alves, David Romeiro Victor and JoãoGuilherme Bezerra Alves*
The World Health Organisation (WHO) and the United Nations International Children’s Emergency Fund (UNICEF) recommend zinc supplementation for children with diarrhea. However, Low and Middle-Income Countries (LMICs) conducted the majority of the studies supporting this recommendation. Although the mortality rate of acute diarrhea in developed countries is low, diarrhea leads to a high number of clinical care and hospital admissions, which represents a significant economic burden. This systematic review assessed the therapeutic benefits of zinc supplementation in the treatment of acute diarrhea in children living in high-income countries. We conducted a literature search on the Medline, Embase, Cochrane, and SciELO databases to find published randomised controlled trials on zinc supplementation and acute diarrhea in children residing in developed countries. We conducted a systema.. View More»
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