Spanish Chinese Russian German French Japanese Portuguese Hindi Telugu Tamil
Flyer

Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
  • Journal h-index: 18
  • Journal CiteScore: 4.35
  • Journal Impact Factor: 3.75
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
PMC/PubMed Indexed Articles

Heritability of Hippocampal Formation Sub-region Volumes

Google Scholar citation report
Citations : 1528

Journal of Neurology and Neuroscience received 1528 citations as per Google Scholar report

Flyer image
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • The Global Impact Factor (GIF)
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Google Scholar
  • Secret Search Engine Labs
View More
Share This Page

Evidence for a causal contribution of macaque vestibular, but not intraparietal cortex to heading perception

4th EuroSciCon Conference on Neurology & Neurological Disorders
July 12 -13, 2018 Paris , France

Aihua Chen, Gregory C DeAngelis and Dora E Angelaki

East China Normal University, Shanghai, China Brain and Cognitive Sciences, University of Rochester, New York, USA Baylor College of Medicine, Texas, USA

Posters & Accepted Abstracts: J Neurol Neurosci

Abstract:

Multisensory convergence of visual and vestibular signals has been observed within a network of cortical areas that are involved in representing heading. Vestibular-dominant heading tuning has been found in the macaque parieto-insular vestibular cortex (PIVC) and adjacent visual posterior sylvian area (VPS), whereas relatively balanced visual/vestibular tuning was encountered in the ventral intraparietal (VIP) area and visual-dominant tuning was found in the dorsal medial superior temporal (MSTd) area. Although the respective functional roles of these areas remain unclear, perceptual deficits in heading discrimination following reversible chemical inactivation of area MSTd suggested that areas with vestibular-dominant heading tuning also contribute to behaviour. To explore the roles of other areas in heading perception, muscimol injections were used to reversibly inactivate either macaque PIVC or VIP bilaterally. Inactivation of anterior PIVC increased psychophysical thresholds when heading judgments were based on either optic flow or vestibular cues, although effects were stronger for vestibular stimuli. All behavioural deficits recovered within 36 hours. Visual deficits were larger following inactivation of the posterior portion of PIVC, likely because these injections encroached upon VPS, which contains neurons with optic flow tuning (unlike PIVC). In stark contrast, VIP inactivation led to no behavioural deficits, despite the fact that VIP neurons show much stronger choice-related activity than MSTd neurons. These results suggest that area VIP either provides a parallel and partially redundant pathway for this task, or does not participate in heading discrimination. In contrast, PIVC/VPS, along with MSTd, make causal contributions to heading perception based on either vestibular or visual signals.

PDF HTML