T Al Ani, I Grecu, S Wimbush and M Dryden
Dumfries and Galloway Royal Infirmary, UK Royal Hampshire County Hospital, UK
Posters & Accepted Abstracts: Arch Clin Microbiol
This case report describes the intravesical use of a novel antimicrobial agent: Surgihoney®. The ROS hydrogen peroxide in Surgihoney® exhibits antimicrobial action by a reaction with thiol groups in enzymes, proteins, DNA and bacterial cell membranes. It is highly antimicrobial against gram positive and negative bacteria, viruses and fungi and breaks down biofilms. A 62 year old paraplegic patient with long term supra pubic catheter required 12 hospital admissions between January and June 2017 due to recurrent cystitis that was treated with multiple courses of intravenous antibiotics and bladder washout. To prevent recurrent infections a three week trial of intravesical Surgihoney® was used. 100 grams diluted with 50 ml 0.9% saline was injected once a week in the community through the suprapubic catheter and clamped for one hour after each injection. Written patient consent was obtained for abstract writing and publication. Following three weeks Surgihoney® treatment urine culture was sterile. Patient was put on long term Surgihoney® treatment and did not require any hospital admissions from June until the time of abstract writing in October 2017. Surgihoney® is an extremely promising agent in the treatment of recurrent bladder infections.
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