Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Kazakhstan
Short Communication
Preliminary results of the study of polymorphisms associated with remodeling of the myocardium and carotid arteries in hypertension in the Kazakh population
Author(s): Ainur Sibagatova*
Introduction: Cardiovascular Disease (CVD) is the leading cause of death in Kazakhstan. In the structure of CVD, hypertension takes the first place and leads to remodeling of the myocardium and carotid arteries, which significantly increases cardiovascular risk. A number of studies have been carried out that established the genetic characteristics associated with the risk of hypertension and target organ damage in hypertension, but not in Kazakh population.
The aim of this project is to study the molecular genetic predictors of remodeling of the cardiovascular system in HTN in Kazakh population.
Materials and methods: The sample size is 1000 people. There were 4 groups of 250 hypertensive individuals, age - up to 61 years.
Group without remodeling with carotid artery remodeling (CR), intima-media complex (IMC) > 0.9 mm.. View More»