Department of Molecular Biology, University Of Gujarat, India
Mini Review
Enzymes and Drug Targets: Current Advances and Future Perspectives
Author(s): Ashutosh Mukharji*
Enzymes play pivotal roles in various cellular processes, making them
attractive targets for drug development. Over the years, significant
advances have been made in the identification and characterization
of enzymes as potential drug targets. This review explores the current
state of knowledge on enzymes as drug targets, highlighting recent
developments in enzyme-targeted therapeutics and the challenges
in drug discovery and development. We discuss the intricacies of
enzyme inhibition, allosteric regulation, and modulatory mechanisms
that influence drug efficacy and selectivity. Moreover, we delve into
the emerging technologies and approaches, such as computational
modeling and high-throughput screening that have revolutionized
the identification of novel enzyme targets. Furthermore, we explore
the potential of personalized medicine in enzyme-targe.. View More»