General Physician, Universidad Militar Nueva Granada, Bogota, Colombia
Review Article
Relationship between Acral Lentiginous Melanoma and Exposure to UV Radiation
Author(s): Laura Camila Garcia Medina*, Maria Patricia Gamero Tafur, Maria Camila Marin Murillo, Yinneth Yasmin Ruiz Atencio, Rosa Angelica Osorio Burgos, Diana Lizeth Grajales Trujillo, Catalina Maria Gutierrez Pico and Jonathan Oscar Reyes Padron
Background: Acral melanoma is a melanoma that occurs on the hands and feet, represents 2 to 3% of all new melanomas, for its diagnosis a narrow margin excisional biopsy is recommended. Ultraviolet radiation is classified as a complete carcinogen, because it is both a mutagen and a non-specific damaging agent and has both tumor initiator and tumor promoter properties.
Methodology: A narrative review was carried out through various databases from January 2009 to January 2022; the search and selection of articles was carried out in journals indexed in English. Keywords were used: Melanoma, Acral, and Ultraviolet.
Results: Acral Lentiginous Melanoma, like mucosal melanomas, is a subtype of melanoma with low mutational load and does not present mutations induced by ultraviolet radiation that are commonly observed in oth.. View More»
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