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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 51
  • Journal CiteScore: 46.50
  • Journal Impact Factor: 26.99
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Cosmin Constantin Oprea

Independent Research, Bucharest Romania, Romania

Publications
  • Research Article   
    The Role of Myeloid - Derived Suppressor Cells (MDSCs) in the Immune Response Regarding Hepatitis C
    Author(s): Cosmin Constantin Oprea*

    Purpose of Review: ,?????? C virus ?n??c??n and the immune response in babies and adults. Findings: The presence of MDSCs in new-borns makes ,?????? C chronic in the ???? years of life in the case of exposure to virus. The expansion of MDSCs allows the immune system to maintain the chronic ?n??c??n with ,?????? C because MDSCs are responsible for the ?????nc??n of the immune system and not the virus itself. MDSCs express CTLA-4, who is a protein receptor that ??nc??n? as an immune checkpoint and downregulates immune responses. The expression of the CTLA-4 protein in the lymph node allows the m?n????????n of ??????? C and allows the ?n??b???n of T cells against HCV RNA. .. View More»

    Abstract PDF