Bio analytical Core Group, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, USA
Mini Review
Drug Development for Cancer Treatment
Author(s): David Ross*
To provide the RNA and protein complexity needed to control gene expression,
RNA editing is essential. Correct RNA editing preserves organism development
and cell function. Diseases and cancer may result from an imbalance in the
RNA editing machinery. Though few studies have been reported in the realm of
natural products that target RNA editing for disease and cancer therapy, it has
recently been acknowledged as a target for drug discovery. Therefore, medicinal
natural compounds may be able to target RNA editing. We present a literature
summary of the biological effects of RNA editing on gene expression, illnesses,
malignancies, and medications in this study. Additionally, a summary of the RNA
editing bioinformatics resources was provided.
Keywords
Drug discovery; Drug Development; Cancer therapy; RNA editing;
Bioinformatics .. View More»
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