UNICANCER, Institut Paoli-Calmettes, Department of Radiation Oncology, 13009 Marseille, France
Expert Review
Natural history of COVID-19 and Coronavirus Disease
Author(s): Gibran Mark*
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that caused
the COVID-19 pandemic and emerged in late 2019 still lacks a vaccine, despite
intensive research. One of the most pressing issues affecting global public health
is this transmissible disease. Infection prevention and control measures involving
supportive care, such as supplemental oxygen and mechanical ventilation, have
been the sole focus of COVID-19 clinical management. In the meantime, research
is going on to find a treatment that works to stop the virus from spreading, reduce
symptoms, extend life expectancy, and lower mortality rates. Based on the body
of clinical knowledge gathered from infected patients regarding the natural history
and evolution of the infection, a number of drug classes, many of which are already
used to treat other diseases, are being evaluated.
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