Graduate Program in Bioinformatics - SEPT, Federal University of Paraná, Brazil
Review Article
How the endocrine system and microbiota explain the emotions biochemistry and their impact in health
Author(s): Guilherme Linhare*, Elsa S Lima, Camila P Perico, Antonio C Da Silva Filho, Camilla R De Pierri, Roberto T Raittz, Dieval Guizelini and Jeroniza N Marchaukoski
Emotional reactions stimulate neural circuits and biological pathways that produce neurotransmitters, affecting homeostasis and promoting disease. Health and emotions communicate, establishing a bidirectional cause-and-effect pathway. The composition of the microbiota also affects health and emotions, interacting through metabolites, such as short-chain fatty acids (SCFA), with the host's biochemistry. Certain genera of bacteria act in different ways on the host's homeostasis, keeping the immune system constantly vigilant and acting on the synthesis of neurotransmitters, such as serotonin and dopamine, which are responsible for well-being. When the host is in homeostasis, the synthesis of neurotransmitters is normal, which keeps the intestinal microbiota in balance. However, when the organism is out of balance, this synthesis is impaired; decreasing the concentration of the in.. View More»
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