Department of Neuroradiology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Melatonin protects E. coli neurons the intestinal microbiota influences meningitis
Author(s): Guoqiang Zhang*
Avian meningitis Escherichia coli(E. coli) can beget acute bacterial
meningitis which threatens flesh health, causes great profitable
losses in the flesh assiduity, and has lately been suspected as
a implicit zoonotic pathogen. Melatonin can offset bacterial
meningitis- convinced dislocation of the blood – brain hedge( BBB),
neuroinflammation, and reduce mortality. There are adding data
showing that melatonin’s salutary goods on bacterial meningitis
are associated with intestinal microbiota. In this study, our data
showed that melatonin soothed neurological symptoms, enhanced
survival rate, defended the integrity of the BBB, reduced the bacterial
cargo in colorful apkins and blood, and inhibited inflammation and
neutrophil infiltration of brain towel in an APEC TW- XM- meningitis
mice model. The results of 16S rRNA showed tha.. View More»
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