Department of Translational Epidemiology, Sorbonne University, Paris, France
Editorial
Artificial intelligence in COVID-19 drug repurposing
Author(s): Iman Beheshti*
Drug repurposing or repositioning may be a technique
whereby existing drugs are wont to treat emerging and
challenging diseases, including COVID-19. Drug
repurposing has become a promising approach due to
the chance for reduced development timelines and
overall costs. The artificial intelligence (AI) pioneers of
the 1950s foresaw building machines that would sense,
reason, and think like people?a proof-of-concept
referred to as general AI. The increasing cost of drug
development is thanks to the massive volume of
compounds to be tested in preclinical stages and
therefore the high proportion of randomised controlled
trials (RCTs) that don't find clinical benefits or with
toxicity issues. This Review provides a robust rationale
for using AI-based assistive tools for drug repurposing
medications for human disease, including during the
COVID-19 pandemic. Drug repurposing may .. View More»