Department of Biotechnology, YBN University, Ranchi, Jharkhand, India
Research
Antiproliferative effect of Ocimum sanctum Against Benzo[A]pyrene Induced Lung Tumours in Rats
Author(s): Arun Kumar*, Jyotsna Sethi and Chandrajeet Kumar
The disease of lung has increased many folds in the recent times. Unfortunately, the lung cancer disease cases have also been reported many times. Although smoking tobacco products are thought to be the causative agents. But the environmental pollution has elevated the disease risk. Among the common carcinogens, Benzo [A]pyrene is one of the known carcinogens which is directly responsible for the cause of the disease. It is a member of polycyclic aromatic hydrocarbon group and is usually generated during the partial burning of organic matter. Benzo (a) pyrene has been shown to inflict damage on the lungs as well as liver. Thus, the present study has been aimed to study the anticancer activity of Ocimum sanctum leaf extract on Benzo [A]pyrene induced lung cancer in rats. Male Charles Foster rats, 6 weeks old weighing around (150-180 g) were used for the study and were induced Benzo[A] .. View More»