Department of Entomology, University of California, United States
Editorial
Evolutionary Insights into Enzymes: Unraveling the Molecular History of Biological Catalysts
Author(s): Manvi Gupta*
Enzymes, as biological catalysts, play a pivotal role in driving the myriad
of chemical reactions essential for life. Understanding their evolutionary
history offers critical insights into the molecular mechanisms that
have shaped their catalytic functions and diversified their roles across
organisms. This review delves into the evolutionary journey of enzymes,
focusing on how the interplay of genetic mutations, gene duplications,
horizontal gene transfers, and natural selection has sculpted their
structures and functions over time. In this comprehensive examination,
we explore the ancient origins of enzymes and trace their evolutionary
paths through geological epochs, uncovering early enzyme prototypes
that emerged in primordial environments. The integration of molecular
phylogenetic, comparative genomics and structural biology has
provided invalua.. View More»