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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 51
  • Journal CiteScore: 46.50
  • Journal Impact Factor: 26.99
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Mohammad Oves

Department of Biotechnology, High Institute of Biotechnology of Sidi Thabet, University of Manouba, BP-66, 2020 Ariana, Tunis, Tunisia

Publications
  • Mini Review   
    Development of Nonionic Bisphosphonate-Modified Drug-Loaded Nanoparticles Binding to Hydroxyapatite
    Author(s): Mohammad Oves*

    Developing drug-loaded nanoparticles that bind to hydroxyapatite (HA) and can be used to make bone graft substitutes that release medications or growth hormones was the aim of this research. To do this, the non-ionic surfactant Brij 78 (polyoxyethylene (20) steady ether) was first modified using pamidronate (Pa). Pa-Brij 78 was used as a surfactant and an affinity ligand to HA to construct three different types of Pa surface functionalized nanoparticles: solid lipid nanoparticles (Pa-SNPs), nanoemulsions (Pa-NEMs), and PLGA nanoparticles (Pa- PNPs). The model drug curcumin was successfully encapsulated using the three nanoparticles. Pa-NEM, Pa-PNP, and Pa-SNP all had widths of about 150 nm and polydispersity indices (PDIs) less than 0.20. The drug encapsulation efficiency rates of the three nanoparticles were all greater than 85%. Additionally, this order was determined by the nanopar.. View More»

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