Department of Biochemistry, Zakariya University Multan, Punjab, Pakistan
Research Article
Synthesis, Characterization, and Antibacterial Activity two New Schiff Bases devired from (E)-2-(((2-aminoethyl) imino) methyl) phenol (E)-2-(4-aminobut-1-enyl)-5-methylbenzamine
Author(s): Sheheryar* and Mohib Ullah Shah
In this study two new Schiff base ligands were synthesized, characterized and antibacterial activities were investigated against Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, Salmonella typhimurium, and Staphylococcus aureus. (E)-2-(4-aminobut-1-enyl) phenol derived from Ethylene diamine and Salicyldehye. (E)-2-(4-aminobut-1-enyl)-5-methylaniline derived from 4-dimethyl amino benzaldehyde and Ethylene di-amine. The Schiff bases were characterized by elemental analysis and FT-IR. The Schiff base ligands were screened in vitro for their antibacterial inhibiting potential by using Disc diffusion method. The results indicated that the Schiff base I have showed biological activity against E coli. The main purpose of the study was to compare the inhibitory effect of these Schiff bases with commercial antibiotics Ciprofloxacin an.. View More»
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