University Hospital of South Manchester NHS Foundation Trust, University of Birmingham, UK
Case Report
Induction Chemotherapy for Cancer of Mandibular Gingival in a Patient with Solitary Kidney
Author(s): Mothe BS* and Davison IW
Solitary kidney is congenital or acquired, and the main cause of the latter includes nephrectomy. Regardless of the causes, individuals with a solitary kidney may have renal dysfunction. However, limited data on antineoplastic effects on renal function are available in chemotherapy for head and neck cancer. In this report, we describe a case of a solitary kidney patient with mandibular gingival cancer who was treated with induction chemotherapy and surgery. A 55-year-old Japanese woman was referred to us with a persistent pain in the left mandible that lasted for a few months. Her medical history included right nephrectomy after a traffic accident in childhood. An incisional biopsy revealed well-differentiated squamous cell carcinoma. The patient was diagnosed with stage G3a chronic kidney disease. She underwent two cycles of induction chemotherapy with docetaxel, cisplatin, and 5-flu.. View More»
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