Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
Mini Review
Targeting Tumour Blood Vessels with a Liposomal Drug Delivery system for Cancer Treatment
Author(s): Naghmeh Shahraki*
By providing various drug delivery methods and controlled-release distribution
tactics, nanotechnology provides an alternative to traditional treatment
alternatives. Due to their high biodegradability and general lack of toxicity,
liposomes provide a flexible platform for a number of various delivery strategies
that may improve the distribution and targeting of medicines to tumours. Due
to fenestrated blood arteries within tumours, liposomes spontaneously enter
tumours, causing recognised increased permeability and associated medication
retention effects. Liposomes are appealing carriers for molecular imaging
applications because they can be utilised to transport radioactive moieties, such
as radiotracers, which can be bound at various points inside liposomes. Using
the phage display method, various high-affinity and selectivity peptides can be
deliver.. View More»