Department of Toxicology, University of Medicine and Pharmacy of Craiova, Craiova, Romania
Review Article
Neurotoxicology: Unraveling the Complex Interplay between Chemicals and the Nervous System
Author(s): Robert Wenig*
Neurotoxicology is a multidisciplinary field that investigates the adverse
effects of chemical agents on the nervous system. This review delves into
the intricate relationship between various chemicals and neural health,
exploring mechanisms of neurotoxicity, associated health impacts,
and assessment strategies. Neurotoxic agents, including heavy metals,
pesticides, industrial chemicals, and pharmaceuticals, disrupt neural
function through mechanisms such as oxidative stress, neurotransmitter
system interference, and inflammation. Cutting-edge techniques like
stem cell-derived models and neuroimaging facilitate the assessment
of neurotoxicity. By enhancing our understanding of these complex
interactions, neurotoxicology contributes to informed risk management
and the development of safer chemicals, safeguarding neurological wellbeing.
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