Department of Neurological Sciences, University College London, London, UK
Mini Review
The role of microglia in neuroinflammation and neurodegenerative diseases: Mechanisms and therapeutic targets
Author(s): Robert Wilson*
Microglia, the resident immune cells of the central nervous system,
play a crucial role in neuroinflammation and the progression of
neurodegenerative diseases. This review explores the role of microglia
in neuroinflammation and neurodegenerative diseases, focusing
on the underlying mechanisms and potential therapeutic targets.
We discuss the activation and polarization states of microglia, the
release of pro-inflammatory and anti-inflammatory factors, and
the interactions with other cell types in the brain. Furthermore, we
highlight the emerging therapeutic strategies aimed at modulating
microglial function, including targeting microglial activation,
polarization, and phagocytic activity. Understanding the complex role
of microglia in neuroinflammation and neurodegenerative diseases
is critical for the development of effective therapeuti.. View More»
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