Division of Cancer Biology, the Institute of Cancer Research, London, UK
Research Article
Phosphoproteomics in translational research: a cancer perspective
Author(s): Ronald Grane*
Phosphoproteomics has been extensively used as a diagnosing analysis tool to characterize the phosphorylated parts of the cancer protein. Advances within the field have yielded insights into new drug targets, mechanisms of sickness progression and drug resistance, and biomarker discovery. However, application of this technology to clinical analysis has been difficult as a result of sensible problems with reference to specimen integrity and neoplasm nonuniformity. On the far side these limitations, phosphoproteomics has the potential to play a polar role in translational studies and contribute to advances in several neoplasm teams, together with rare sickness sites like cancer. During this review, we have a tendency to propose that deploying phosphoproteomic technologies in translational analysis could facilitate the identification of higher outlined prognostic biomarkers for patient s.. View More»