Department of Entomology, University of University of Maryland, United States
Mini Review
Enzyme Inhibitors: Strategies and Challenges in Drug Design
Author(s): Sakshi Singh*
Enzyme inhibitors have emerged as powerful therapeutic agents in drug discovery and development. Targeting specific enzymes involved in disease-related pathways provides opportunities for modulating biological processes and treating various disorders. This review explores different strategies and challenges in the design of enzyme inhibitors for therapeutic purposes. The study begins by highlighting the importance of enzyme inhibition as a strategy for modulating enzyme activity and interfering with disease processes. Enzyme inhibitors can exert their effects by blocking the active site of the enzyme, disrupting cofactor binding, or interfering with protein-protein interactions crucial for enzyme function. These inhibitors can be classified into different categories based on their mechanism of action, including reversible and irreversible inhibitors, competitive and non-competitive in.. View More»
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