Department of Molecular Genetics, University of Brown, Providenc, United States
Short Communication
Targeting the Enemy within: HIV Drug Targets and Therapeutic Strategies
Author(s): Santip Panday*
The Human Immunodeficiency Virus (HIV) remains a global
health challenge, with over 38 million people living with the
virus worldwide. The development of effective antiretroviral
therapies has revolutionized HIV management, transforming
the infection from a once debilitating disease to a chronic
condition. This article explores the diverse landscape of HIV
drug targets and therapeutic strategies, highlighting the
ongoing efforts to combat the virus and improve patient
outcomes. HIV infects CD4+ T cells, macrophages and
dendritic cells, hijacking the host cellular machinery to
replicate and spread. The discovery of key viral enzymes, such
as reverse transcriptase, integrase and protease, has paved
the way for targeted drug development. Antiretroviral drugs
inhibiting these viral enzymes have become the cornerstone
of HIV therapy, eff.. View More»
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