Professor Emeritus, Colleges of Engineering and Health Sciences, University of Wisconsin, Milwaukee, WI, USA
Research Article
The Cole Relaxation Frequency as a Parameter to Identify and Spatially Map Cancer in Breast Tissue: Preliminary In Vivo Patient Study
Author(s): William D Gregory*, Shahila Mehboob Christie, Christopher W Gregory, James J Marx, John Shell and Wendy Mikkelson
We have previously reported successful classification of breast cancer vs. benign breast tissue
using Cole Relaxation Frequency (CRF) values calculated from impedance measurements on
ex-vivo breast tissue samples at the time of surgery. Subsequent analysis of outcomes from
follow-up medical visits of patients from this cohort provided evidence that the CRF values
measured for tissue determined to be cancerous at the time of surgery correlated well with
three possible outcomes for the patients (No Recurrence of Cancer; Recurrence with No
Metastasis; and Recurrence with Metastasis). We present here data from a small (n=50)
IRB approved study to classify and spatially map cancer and benign regions in the breast in
vivo. Apparatus consisting of two parallel plates mounted on a conventional mammography
gantry was used for these measurements. A portion of one of t.. View More»
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