Department of Pharmaceutics, Shankersinh Vaghela Bapu Institute of Pharmacy, Gujarat Technological Pharmacy, Vasan, Gandhinagar, Gujarat, India
Research Article
Transdermal Drug Delivery Systems Enhancement in Skin Permeation Using Electroporation and Gold Nanoparticle
Author(s): Shanaya K*
To compare the performance differences between transdermal products, in vitro drug release tests are often utilised and mandated by numerous authorities. The outcome, however, is insufficient to make a reliable prediction of the drug release in vivo. The traditional USP apparatus 2 and 5 methods and a new approach for assessing drug release from patches have both been investigated in this study. On a synthetic skin simulator, durogesic patches—used here as a model patch—were applied, and three moisture levels (29, 57, and 198 L cm2) were assessed. The artificial skin simulators were taken out at 1, 2, 3, 4, 6, and 24 hours and removed.. View More»
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