Department of Biotechnology, SR Group of Institutions, Lucknow, India
Mini Review
Exploring the Role of Glycolysis in Cancer Metabolism: Implications for Rigid Therapies
Author(s): Smrity Yadav*
Cancer metabolism has emerged as a crucial determinant in tumor
development and progression, with dysregulated metabolic pathways
supporting the energy demands of rapidly proliferating cancer cells.
Among these metabolic alterations, glycolysis, a process that converts
glucose into pyruvate, has gained significant attention due to its
unique impact on cancer cell survival and proliferation. In this study,
we investigate the pivotal role of glycolysis in cancer metabolism and
explore its potential implications for targeted therapies. Through in vitro
analyses, we demonstrate that cancer cells exhibit enhanced glycolytic
activity, a hallmark feature of the Warburg effect, compared to their
normal counterparts. Gene expression analysis reveals upregulation
of key glycolytic enzymes, substantiating the importance of glycolysis
in cancer cells' energy me.. View More»
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