Department of Pharmaceuticals, University of Pittsburgh, Titusville, USA
Review Article
A Review of the ICER Unsupported Price Increase Report and its Potential Use in Health Policy Decisions
Author(s): Roman Casciano*, Matthew Brougham, Ulrich Neumann and Bridget Doherty
Background: The Institute for Clinical and Economic Review
(ICER) recently published its 3rd annual Unsupported Price
Increase (UPI) report and positions it as a guide for policy
making on prescription drug spending. Lawmakers across
the US have shown interest in the UPI approach as a
potential tool to optimize healthcare resource allocation.
Methods: The latest UPI methodology and its changes were
explicitly documented and then compared and contrasted
with the author’s understanding and experience of sound
scientific method and logic.
Results: The UPI report’s findings are based on a partial
product selection and the rejection of high-quality
evidence, offering healthcare decision makers misleading
guidance on the value for money of the assessed products.
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