Zhejiang Gongshang University, China
Research Article
Detection of Specific Anti-Dengue IgM and IgG Antibodies Differentiate Primary from Secondary Infection
Author(s): Zhang Lei*, Yang Feng and WuYanli
Background: The incidence of dengue fever has increased dramatically worldwide in recent decades. Most cases are asymptomatic or mildly symptomatic and recover with self-management, so the actual number of dengue cases is greater than the number reported. Many cases have also been misdiagnosed as other febrile illnesses.
The number of dengue cases reported to World Health Organization (WHO) has increased more than seven-fold over the past 20 years, from 505,430 cases in 2000 to more than 2.4 million in 2010 and 5.2 million in 2019. The number of reported deaths increased from 960 to 4,032 between 2000 and 2015, mainly affecting younger age groups. Between 2020 and 2021, the total number of cases, as well as the number of reported deaths, appears to have decreased. However, data in this area are incomplete and the COVID-19 pandemic may also have hindered case.. View More»
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